DMPQ- Write a short note on gene mapping.

Gene mapping is the sequential allocation of loci to a relative position on a chromosome. Genetic maps are species-specific and comprised of genomic markers and/or genes and the genetic distance between each marker. These distances are calculated based on the frequency of chromosome crossovers occurring during meiosis, and not on their physical location

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on the chromosome. There are existing dense genetic marker maps available for humans, and the introduction of next-generation sequencing technologies is facilitating increased construction of genetic maps for other species. Genetic maps are a necessary tool for mapping of disease genes or trait loci, a method also commonly known as linkage mapping. Integrating genetic mapping and disease gene mapping with next-generation sequencing has proven to be a powerful strategy in genetic research.

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