DMPQ- Explain the concept of mitochondrial gene therapy. Discuss how it can play important role in health sector.

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. The recent success of gene therapy across multiple clinical trials has inspired a great deal of hope regarding the treatment of previously intractable genetic diseases. This optimism has been extended to the prospect of gene therapy for mitochondrial disorders, which are not only particularly severe but also difficult to treat. However, this hope must … Read more DMPQ- Explain the concept of mitochondrial gene therapy. Discuss how it can play important role in health sector.

DMPQ- Explain how Indigo cultivation became source of Indian farmer’s exploitation and how farmers resisted against it.

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. By the thirteenth century Indian indigo was being used by cloth manufacturers in Italy, France and  Britain to dye cloth. By the end of the eighteenth century, the demand for Indian indigo grew further.  Britain began to industrialise, and its cotton production expanded dramatically, creating an enormous  new demand for cloth dyes. While the … Read more DMPQ- Explain how Indigo cultivation became source of Indian farmer’s exploitation and how farmers resisted against it.

DMPQ- . Explain the challenges of Kashmir integration and also mention how did India respond to it.

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. In Kashmir, Hari Singh was a Hindu ruler with 75% of Muslim population and he was also averse to idea of joining either India or Pakistan out of his apprehensions regarding both democracy and communalism. Popular political forces led by Sheikh Abdullah wanted to join India on the other hand. India, however, remained non-committal … Read more DMPQ- . Explain the challenges of Kashmir integration and also mention how did India respond to it.

DMPQ- . Discuss the significance of 73rd constitutional amendment act In India’s democracy.

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This act has added a new Part-IX to the Constitution of India. It is entitled as ‘The Panchayats’ and consists of provisions from Articles 243 to 243 O. In addition, the act has also added a new Eleventh Schedule to the Constitution. This schedule contains 29 functional items of the panchayats. It deals with Article … Read more DMPQ- . Discuss the significance of 73rd constitutional amendment act In India’s democracy.

DMPQ- . What is the concept of Metagenomics? Discuss the potential applications of it.

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. Metagenomics is the study of a collection of genetic material (genomes) from a mixed community of organisms. Metagenomics usually refers to the study of microbial communities. “Metagenomics” is the two words “meta” and “genomics”. So genomics is obtaining the DNA sequence, but meta implies that we’re doing it of many organisms together. And metagenomics … Read more DMPQ- . What is the concept of Metagenomics? Discuss the potential applications of it.

DMPQ- What are yamanaka genes. Explain their role in our body.

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Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse and human somatic cells, indicating that these factors regulate the developmental signaling network necessary for ES cell pluripotency. However, systemic analysis of the signaling pathways regulated by Yamanaka factors has not yet … Read more DMPQ- What are yamanaka genes. Explain their role in our body.

DMPQ- . Write a short note on followings: (A) Performance budget (B) Revenue deficit (C) Quantitative Easing

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(A) Performance budget Unlike the traditional line item budget, a performance budget reflects the  goal/objectives of the organization and spells out performance targets. These targets are sought to be achieved through a strategy(s). A Performance Budget gives an indication of how the funds spent are expected to give outputs and ultimately the outcomes. However, performance … Read more DMPQ- . Write a short note on followings: (A) Performance budget (B) Revenue deficit (C) Quantitative Easing

DMPQ- Trace East India company’s response towards 1857 mutiny.

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Company brought reinforcements from England, passed new laws so that the rebels could be convicted  with ease, and then moved into the storm centres of the revolt. Not only the police and military  personnel, but ordinary Britons were empowered to punish the Indians suspected of rebellion.  Rebellion had only one punishment – Death. Delhi was … Read more DMPQ- Trace East India company’s response towards 1857 mutiny.

DMPQ- How did India resolved Hyderabad’s separatist rebellion against Indian state.

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Hyderabad was ruled by Nizam who was autocratic ruler. Indian government even made some concessions when it signed a standstill agreement hoping that Nizam will introduce a representative form of government. But Nizamstarted to expand its military base on encouragement from Pakistan and wanted to take advantage of Indian engagements in Kashmir. Meanwhile, three important … Read more DMPQ- How did India resolved Hyderabad’s separatist rebellion against Indian state.

DMPQ- Discuss the objectives and major features of PESA act of 1996.

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The provisions of Part IX of the constitution relating to the Panchayats are not applicable to the Fifth Schedule areas. However, the Parliament may extend these provisions to such areas, subject to such exceptions and modifications as it may specify. Under this provision, the Parliament has enacted the “Provisions of the Panchayats (Extension to the … Read more DMPQ- Discuss the objectives and major features of PESA act of 1996.

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